22/06/2009, 16:00 — 17:00 — Sala P12, Pavilhão de Matemática
Grant Lythe, Department of Applied Mathematics, University of Leeds (UK)
Stochastic dynamics and T cells
I will discuss Mathematical Immunology, concentrating on T cells. In the first part of the talk, I will consider how a diverse repertoire of T-cell clonotypes is maintained. Understanding the dynamics of "homeostasis" leads to a continuous-time Markov chain model. In the second part of the talk I will discuss timescales for the interaction of T cells with Dendritic cells in a lymph node, which leads to a continuous-space Brownian motion model
